Publications by authors named "M Rottura"
Objective: The purpose of this study was to address the lack of data on the stress and motivation response in master athletes during competitions, as athletic performance in this age group can be significantly impacted by stress rather than appropriate training.
Methods: Coastal rowing beach sprint master athletes aged 43-57 years were examined to assess the saliva levels of stress biomarkers, cortisol, and testosterone. Specifically, samples were collected at awakening and before and after the boat race.
Background: Tirbanibulin 1% ointment has been licensed to treat non-hyperkeratotic actinic keratosis (AK) on the face and scalp in adults. Recent evidence suggests that, besides the antineoplastic effect, tirbanibulin may also confer substantial cosmetic benefits to patients.
Methods: We report a single-center retrospective study of patients affected by solar lentigines (SLs) and AKs in the context of field cancerization treated with tirbanibulin 1% ointment.
The discovery of serine protease proprotein convertase subtilisin-kexin type 9 (PCSK9) has revolutionized pharmacological lipid-lowering treatments. The first PCSK9 antagonists (PCSK9-A), evolocumab and alirocumab, were approved in 2015. Targeting PCSK9 synthesis marked a major advancement in this field, leading to the development of inclisiran, a long-acting siRNA targeting PCSK9 mRNA.
View Article and Find Full Text PDFConventional versus daylight photodynamic therapy for recalcitrant hand warts: Efficacy, safety and recurrence.
Photodiagnosis Photodyn Ther
December 2024
Article Synopsis
- Acral warts, common on hands and feet, can be treated with conventional photodynamic therapy (C-PDT), which has been effective and safe for both adults and children, but the efficacy of daylight photodynamic therapy (DL-PDT) is still unclear.
- A study involving 68 patients aimed to compare the short- and long-term effects of C-PDT and DL-PDT using 10% aminolevulinic acid (ALA) on hand warts, with evaluations of responses occurring at 3 months and 1 year post-treatment.
- Results showed that both treatments were generally effective and well-tolerated, with a majority of patients experiencing excellent responses; however, a notable percentage had warts relapse a year later
Atrial fibrillation (AF) prevalence increases in older patients which also show a high thromboembolic risk. Oral anticoagulants (OACs) are recommended to prevent cardioembolic events and direct oral anticoagulants (DOACs) improved anti-thrombotic treatment. However, the benefits/risks of anticoagulant in older patients still need to be completely defined.
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