Publications by authors named "M Roth-Kleiner"
Background: Day admission surgery (DAS) is meant to provide a better in-hospital experience for patients and to save costs by reducing the length of stay. However, in a prospective payment system, it may also reduce the reimbursement amount, leading to unintended incentives for hospitals.
Methods: Over a 4-month period in 2021 and based on predefined clinical and logistic criteria, patients from different surgical sub-specialties were identified to follow the institutional DAS program.
Article Synopsis
- Pneumothorax (PTX) is a rare but serious condition in neonates, with an overall incidence of 0.56 per 100 births, varying between hospitals; treatment methods included conservative care, chest tube drainage, and needle aspiration.
- Among the treatment options, needle aspiration had a higher failure rate (37%) compared to chest tube drainage (9%), yet it resulted in fewer X-rays and shorter hospital stays (2 days vs 6 days).
- The study proposes a new management algorithm to standardize PTX treatment across different hospitals in the network, aiming to improve outcomes while considering the variability of incidence rates.
Neonatal death represents a major burden in Sub-Saharan Africa (SSA), where the main conditions triggering mortality, such as prematurity, labor complications, infections, and respiratory distress syndrome, are frequently worsened by hypothermia, which dramatically scales up the risk of death. In SSA, the lack of awareness on the procedures to prevent hypothermia and the shortage of essential infant devices to treat it are hampering the reduction of neonatal deaths associated to hypothermia. Here, we offer a snapshot on the current available medical solutions to prevent and treat hypothermia in SSA, with a focus on Kenya.
View Article and Find Full Text PDFLung aging is characterized by lung function impairment, ECM remodeling and airspace enlargement. Tenascin-C (TNC) is a large extracellular matrix (ECM) protein with paracrine and autocrine regulatory functions on cell migration, proliferation and differentiation. This matricellular protein is highly expressed during organogenesis and morphogenetic events like injury repair, inflammation or cancer.
View Article and Find Full Text PDF"Assessing Today for a Better Tomorrow": An observational cohort study about quality of care, mortality and morbidity among newborn infants admitted to neonatal intensive care in Guinea.
PLoS One
November 2021
Background: Neonatal mortality in Guinea accounts for about 30% of all fatalities in children younger than five years. Countrywide, specialized neonatal intensive care is provided in one single clinic with markedly limited resources. To implement targeted measures, prospective data on patient characteristics and factors of neonatal death are needed.
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