Publications by authors named "M Rol"
Despite first-void urine (FVU) being increasingly recognized as a credible specimen for human papillomavirus (HPV) detection, there is a lack of well-validated testing methods providing full quantitative genotyping required for vaccine impact monitoring from FVU samples. The Allplex HPV28 assay, capable of individually detecting 28 HPV genotypes, presents a promising method. We aimed to evaluate its genotype-specific performance on FVU samples, following optimization of FVU preanalytics.
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- The study looks at how sleep, social habits, and the environment affect health in Spain, focusing on the discrepancy between official and solar time.
- The research involved nearly 10,000 participants and used a questionnaire to analyze their sleep patterns, social timing, and environmental factors across work and free days.
- Results showed significant differences in sleep behavior between work and free days, with earlier bedtimes and wake times on workdays, highlighting the impact of societal and environmental cues on individual sleep habits.
Background: Cervical cytology is recommended by WHO as a triage option in HPV-based cervical cancer screening programmes. We assessed the performance of cytology to detect CIN3+ without and with knowledge of HPV positivity.
Methods: Women were screened with cytology and HPV across ESTAMPA study centres in Latin America.
Background: The 2021 World Health Organization (WHO) guidelines on cervical cancer screening and treatment provide countries with evidence-based recommendations to accelerate disease elimination. However, evidence shows that health providers' adherence to screening guidelines is low. We conducted a study in Argentina to analyze health providers' knowledge and perceptions regarding the 2021 WHO Guidelines.
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- Overexpression of HPV oncoproteins E6 and E7 is crucial for cervical cancer linked to HPV, making them potential biomarkers for the disease.
- The study evaluated the OncoE6/E7 test on cervical samples from HPV-positive women, showing variability in positivity rates between HIV-negative women and those living with HIV.
- Operators found the OncoE6/E7 test user-friendly, despite some concerns about its complexity, but caution is advised due to the test's variability and potential for false results, indicating a need for further refinements before widespread use.