Publications by authors named "M Rohla"
Fractional flow reserve (FFR) measurements are recommended for assessing hemodynamic coronary stenosis severity. Intracoronary ECG (icECG) is easily obtainable and highly sensitive in detecting myocardial ischemia due to its close vicinity to the myocardium. We hypothesized that the remission time of myocardial ischemia on icECG after a controlled coronary occlusion accurately detects hemodynamically relevant coronary stenosis.
View Article and Find Full Text PDFBackground: ST-elevation myocardial infarction (STEMI) is a cardiac emergency that requires prompt diagnosis and treatment. We describe a challenging and complex case of managing acute STEMI in a patient with severe anaemia, deranged clotting profile, and infective prodrome.
Case Summary: A 54-year-old Caucasian gentleman was referred by his general practitioner as an emergency after presenting with acute onset of chest pain.
Background: Evidence to support immediate P2Y inhibitor loading in ST-segment elevation myocardial infarction (STEMI) is limited.
Objectives: This study sought to compare outcomes of STEMI patients receiving immediate or delayed P2Y inhibitor treatment.
Methods: Using data from the prospective Bern-PCI registry between 2016 and 2020, we stratified STEMI patients undergoing percutaneous coronary intervention according to time periods with different institutional recommendations regarding P2Y inhibitor pretreatment.
Article Synopsis
- This study investigates the effectiveness of early combination therapy (statin plus ezetimibe) versus statin monotherapy in patients new to lipid-lowering treatments who underwent PCI (stent placement) from 2016 to 2019.
- Findings indicate that while both methods reduced LDL-C levels, the combination therapy led to a larger decrease and a higher percentage of patients achieving the target LDL-C level, especially in those with higher initial levels.
- The researchers suggest that starting high-intensity combination therapy should be the preferred approach for treatment-naïve patients with elevated LDL-C undergoing PCI, as it may offer better results without increasing the rates of major cardiovascular events.