Publications by authors named "M Roesch-Ely"

This study provides a comprehensive investigation of antimicrobial additives (ZnO/AgNPs and SiO/AgNPs) on the properties of biodegradable ternary blends composed of poly(hydroxybutyrate) (PHB), poly(lactic acid) (PLA), and polycaprolactone (PCL) by examining the morphology, thermal stability, crystallinity index, and cell viability of these blends. Overall, transmission electron microscopy (TEM) analysis revealed that AgNPs and SiO exhibited comparable sizes, whereas ZnO was significantly larger, which influences their release profiles and interactions with the blends. The addition of antimicrobials influences the rheology of the blends, acting as compatibilizers by reducing the intermolecular forces between biopolymers.

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A Cu-TiO nanomaterial with unique antibacterial and photocatalytic properties is introduced in this study. Cu-TiO nanocomposites were obtained using an adapted direct current magnetron sputtering apparatus, where TiO anatase nanoparticles (NPs) were used as the substrates and copper as the sputtering target. The obtained powder was characterized by physical and chemical methods.

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The use of platelet-rich plasma (PRP) and adipose-derived stromal cells (ADSC) have been investigated as a form of wound healing enhancement. The objective of this work was to evaluate the association of red propolis (RP) and PRP as inducers of ADSC for application in tissue regeneration. Adipose tissue post-collection and post-cryopreservation was isolated with type II collagenase, characterized by flow cytometry, and differentiated into osteogenic, chondrogenic and adipose cell.

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A new series of compounds planned by molecular hybridization of the nucleobases uracil and thymine, or the xanthine theobromine, with coumarins, and linked through 1,2,3-triazole heterocycles were evaluated for their in vitro anticancer activity against the human tumor cell lines: colon carcinoma (HCT116), laryngeal tumor cells (Hep-2), and lung carcinoma cells (A549). The hybrid compound exhibited better activity in the series, showing an IC50 of 24.19 ± 1.

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Article Synopsis
  • Copper has effective antibacterial properties that can be enhanced with light, making it a viable option for disinfecting surfaces.
  • The study explored both microsized (CuMPs) and nanosized (CuNPs) copper particles, revealing that CuNPs were generally more effective but CuMPs still showed significant biocidal activity, especially under illumination.
  • The findings suggest that CuMPs can serve as a cost-effective alternative for self-cleaning materials in disinfection processes, competing well with smaller nanoparticles.
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