Publications by authors named "M Rodriguez de Molina"
Objective: To assess the association between the combination of corporal adiposity (CA) and cardiorespiratory physical fitness (CRF) with cardiometabolic risk factors in children aged 7-10 years.
Methods: Cross-sectional observational study with a sample of 251 children registered in Family Health Units. Sociodemographic, lifestyle, anthropometric, biochemical, blood pressure, and CRF data were collected.
Background: Chronic obstructive pulmonary disease (COPD) and asthma are the two most prevalent chronic respiratory diseases, significantly impacting public health. Utilizing clinical questionnaires to identify and differentiate patients with COPD and asthma for further diagnostic procedures has emerged as an effective strategy to address this issue. We developed a new diagnostic tool, the COPD-Asthma Differentiation Questionnaire (CAD-Q), to differentiate between COPD and asthma in adults.
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- Major depressive disorder (MDD) is linked to neuroinflammatory processes involving the NLRP3 inflammasome, and a study examined the impact of the NLRP3 rs10754558 polymorphism on MDD diagnoses among young adults.
- A population-based study with 1,100 participants found no significant association between the NLRP3 genotype and MDD diagnosis, but a clinical trial showed that individuals with the GG genotype had poorer treatment outcomes compared to those with GC/CC genotypes.
- Longitudinal analyses indicated that GG individuals experienced less improvement in depressive and anxiety symptoms over time, suggesting that this genotype may affect the effectiveness of psychotherapy for MDD.
Change in leisure-time physical activity and perception of weight gain during the COVID-19 pandemic: results from the ELSA-Brasil Cohort.
Nutr Hosp
December 2024
Objective: this study aimed to identify the association between changes in Leisure-Time Physical Activity (LTPA) and Perceived Weight Gain (PWG) during the COVID-19 pandemic among participants enrolled in the Longitudinal Study of Adult Health (ELSA-Brasil).
Methods: an observational longitudinal study utilizing data from the ELSA-Brasil, Wave 3 - W3 (2017-2019), and Wave-COVID - WC (July/2020 to February/2021). LTPA was assessed using the International Physical Activity Questionnaire, collected at both time points, while PWG was evaluated through a questionnaire in WC.