Innovative Clinical-Organizational Model to Ensure Appropriateness and Quality in the Management of Medical Cannabis: An Italian Regional Case.

This work focuses on the clinical-organizational model implemented in an Italian region (Liguria) to streamline the access procedures to galenic cannabis preparations. The competent local health care authority that takes care of tracing a virtuous path to obtain common, uniform and shared protocols and ensure high standards of care is A.Li.

Bacillus megaterium SF185 spores exert protective effects against oxidative stress in vivo and in vitro.

Endogenous reactive oxygen species (ROS) are by-products of the aerobic metabolism of cells and have an important signalling role as secondary messengers in various physiological processes, including cell growth and development. However, the excessive production of ROS, as well as the exposure to exogenous ROS, can cause protein oxidation, lipid peroxidation and DNA damages leading to cell injuries. ROS accumulation has been associated to the development of health disorders such as neurodegenerative and cardiovascular diseases, inflammatory bowel disease and cancer.

Adsorption-induced slip inhibition for polymer melts on ideal substrates.

Hydrodynamic slip, the motion of a liquid along a solid surface, represents a fundamental phenomenon in fluid dynamics that governs liquid transport at small scales. For polymeric liquids, de Gennes predicted that the Navier boundary condition together with polymer reptation implies extraordinarily large interfacial slip for entangled polymer melts on ideal surfaces; this Navier-de Gennes model was confirmed using dewetting experiments on ultra-smooth, low-energy substrates. Here, we use capillary leveling-surface tension driven flow of films with initially non-uniform thickness-of polymeric films on these same substrates.

Universal contact-line dynamics at the nanoscale.

The relaxation dynamics of the contact angle between a viscous liquid and a smooth substrate is studied at the nanoscale. Through atomic force microscopy measurements of polystyrene nanostripes we simultaneously monitor both the temporal evolution of the liquid-air interface and the position of the contact line. The initial configuration exhibits high curvature gradients and a non-equilibrium contact angle that drive liquid flow.

Surface Fraction Dependence of Contact Angles Induced by Kinks in the Triple Line.

On periodic superhydrophobic surfaces the receding contact angle often scales with the surface fraction, as expected from a simple rule of mixture, the Cassie relation. However, it has been argued that energy averaging breaks down owing to line pinning, and that line fraction scaling should apply instead. From experiments and simulations we show that proper inclusion of triple line defects introduce surface fraction scaling in the line depinning threshold.