Ileal Predominance in Crohn's Disease Is Associated With Increased Intestinal Surgery and Biological Therapy Use, With Lower Treatment Persistence.

Introduction: Crohn's disease (CD) varies by location, potentially affecting therapy efficacy and surgery risk, although research on this topic is conflicting. This study aims to investigate the independent association between CD location and therapeutic patterns.

Methods: We analyzed patients with CD diagnosed from January 2005 to May 2023 registered in the nationwide ENEIDA registry.

Factorial designs are accurate tools to pick up the most promising extremophiles for future biosurfactant production.

In this study, five strains previously isolated from black liquor (BL) and vinasse (V) were tested to assess the most promising regarding its capacity of biosurfactant production. For that, four factorial designs of two factors at two levels (2) were run for each strain. Selected factors were the production time and the composition media, while the surface tension reduction and optical density were the responses variables.

Transcultural validation of the risk assessment and predictor tool (RAPT) to Spanish.

Objective: Translation and validation of the risk assessment and prediction tool (RAPT) into Spanish to assess the discharge needs of patients after total hip arthroplasty.

Methodology: The original RAPT instrument was translated into Spanish following the guidelines of Sousa and Rojjanasrirat, 2011. To carry out the cross-cultural adaptation of the instrument to Spanish, the translation method of Guillermin et al.

Being a Pakistani mother in Catalonia: a mixed methods study.

Introduction: In Pakistani migrant families, contextual transformation can affect adult caregivers' parental skills and their ability to exercise positive parenting. We focused on identifying and describing patterns, practices and beliefs about parenting, identifying differential characteristics between the context of origin and the host context, and exploring Pakistani immigrants' use of resources or assets in the area of parenting support.

Methods: Participants consisted of 20 women, established in Catalonia, Spain (<5 years of residence) who have children (at least one of preschool-age).

Cytotoxic effects of ivermectin on : induction of apoptosis and cell cycle arrest.

Introduction: is a flagellated protozoan parasite causing giardiasis, a common intestinal infection characterized by diarrhea, abdominal cramps, and nausea. Treatments employed to combat this parasitic infection have remained unchanged for the past 40 years, leading to the emergence of resistant strains and prompting the search for new therapeutic agents.

Methods: This study investigated the cytotoxic effects of ivermectin (IVM) on trophozoites.