Adherence to the dietary approaches to stop hypertension (DASH) and risk of pancreatic steatosis.

Background: The Dietary Approach to Stop Hypertension (DASH) has shown positive effects on various health factors that may be related to pancreatic steatosis (PS). This study aimed to investigate the association between adherence to the DASH diet and the risk of developing PS.

Methods: This case-control study was conducted on 278 patients diagnosed with gallstone disease and referred to Taleghani Hospital (Tehran, Iran).

Clinical outcome of surgically treated displaced acetabular fractures with central dislocation using combined anterior and medial plating.

Aim: Acetabular fractures are complex articular fractures with a big challenge for orthopaedic surgeons. Surgically managed displaced fractures carry favourable outcomes, especially if the articular surface is reduced accurately. This study aims to assess the clinical outcomes of surgically fixed displaced acetabular fractures with central dislocation using combined anterior and medial plating.

The association between plant-based diet indices and risk of mortality in patients with cirrhosis: a cohort study.

Background: Following a plant-based diet is associated with a wide range of health benefits. The current study aimed to investigate the association between plant-based diet indices, specifically the plant-based diet index (PDI), healthful PDI (hPDI), and unhealthful PDI (uPDI) and risk of mortality in cirrhotic patients.

Methods: This cohort study included a total of 121 patients with cirrhosis, who were followed for four years.

Methodological approaches in developing and implementing digital health interventions amongst underserved women.

Background: Minority populations are utilizing mobile health applications more frequently to access health information. One group that may benefit from using mHealth technology is underserved women, specifically those on community supervision.

Objective: Discuss methodological approaches for navigating digital health strategies to address underserved women's health disparities.

STING pathway as a cancer immunotherapy: Progress and challenges in activating anti-tumor immunity.

The stimulator of the interferon genes (STING) signaling pathway plays a crucial role in innate immunity by detecting cytoplasmic DNA and initiating antiviral host defense mechanisms. The STING cascade is triggered when the enzyme cyclic GMP-AMP synthase (cGAS) binds cytosolic DNA and synthesizes the secondary messenger cGAMP. cGAMP activates the endoplasmic reticulum adaptor STING, leading to the activation of kinases TBK1 and IRF3 that induce interferon production.