Publications by authors named "M Rentzos"
Screening for SCA27B, CANVAS and other repeat expansion disorders in Greek patients with late-onset cerebellar ataxia suggests a need to update current diagnostic algorithms.
J Neurol Sci
December 2024
Objective: Late-onset cerebellar ataxia (LOCA) is a slowly progressive cerebellar disorder with symptom onset ≥30years of age. Intronic tandem repeat expansions (TREs) in RFC1 and FGF14 have recently emerged as common causes of LOCA. The relative contribution of classic vs.
View Article and Find Full Text PDFIntroduction Peripheral neuropathy is a well-known manifestation of alcohol overconsumption, but neurophysiological confirmation of peripheral nerve damage is costly and sometimes involves invasive procedures. The aim of this study was to investigate the ability of commonly used clinical scales to detect the presence of neuropathy in patients with alcohol use disorder (AUD). Methods Data were collected retrospectively on 116 patients diagnosed with AUD and treated voluntarily in a detoxification special unit.
View Article and Find Full Text PDFArticle Synopsis
- The study examined peripheral nerve damage in 90 patients with Alcohol Use Disorder (AUD) over three years, focusing on clinical and neurophysiological findings.
- 54% of subjects were diagnosed with peripheral neuropathy, with varying types including large fiber neuropathy (LFN) and small fiber neuropathy (SFN).
- Higher scores on neuropathy assessments correlated with nerve function decline, and a longer duration of alcohol use was linked to more severe neuropathy symptoms, suggesting that clinical scales can be effective for assessing neuropathy when neurophysiological tests are unavailable.