Publications by authors named "M Renke"
Article Synopsis
- * Severe malaria can lead to serious health problems, and intravenous artesunate is recommended for treatment, especially in areas where malaria is not commonly found.
- * A case study of a seafarer illustrates potential complications from malaria treatment, emphasizing the importance of prophylactic measures for travelers and the need for ongoing monitoring after treatment to catch late complications like post-artesunate haemolysis.
The clinical context of drug interactions detected by automated analysis systems is particularly important in older patients with multimorbidities. We aimed to provide unique, up-to-date data on the prevalence of potentially inappropriate medications (PIMs) and drug-drug interactions (DDIs) in the Polish geriatric population over 80 years old and determine the frequency and the most common PIMs involved in DDIs. We analyzed all non-prescription and prescription drugs in a representative national group of 178 home-dwelling adults over 80 years old with excessive polypharmacy (≥10 drugs).
View Article and Find Full Text PDFBackground: Depressive disorder is common among haemodialysis patients. The purpose of this study was to explore approaches to diagnosing depression in the context of a real-life setting, with the view of creating practical recommendations. It also aimed to evaluate the prevalence of depression and dementia.
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- * A total of 78 adult patients were screened for depressive symptoms, with 9 diagnosed cases receiving either sertraline or agomelatine over a 24-week observation period; sertraline proved effective while agomelatine did not lead to remission.
- * Mild side effects were reported with both medications, with no serious complications or significant liver enzyme abnormalities noted, highlighting the need for further research on depression treatments for hemodialysis patients.
Hyperexcitability in sensory neurons is known to underlie many of the maladaptive changes associated with persistent pain. Chemogenetics has shown promise as a means to suppress such excitability, yet chemogenetic approaches suitable for human applications are needed. PSAM-GlyR is a modular system based on the human α7 nicotinic acetylcholine and glycine receptors, which responds to inert chemical ligands and the clinically approved drug varenicline.
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