Publications by authors named "M Regmi"

Introduction: Timely institution of pre-hospital therapies aimed at damage control and the appropriately timed decision of transfer to higher centers for definitive neurosurgical management are crucial in determining the outcome of patients following traumatic brain injury. This study aimed to evaluate the factors determining pre-hospital care and delay in patients with traumatic brain injury.

Methods: This was a descriptive cross-sectional study conducted in a tertiary care center after obtaining ethical approval from the Institutional Review Board (approval number 392 (6-11) E2).

View Article and Find Full Text PDF
Article Synopsis
  • Spinal disorders affect nearly 5% of the global population and lead to significant socioeconomic costs, highlighting a critical health issue.
  • Neurosurgery has transformed from basic techniques to advanced minimally invasive methods, now incorporating technologies like robotic assistance and advanced imaging for enhanced precision.
  • This review focuses on innovations in imaging, biomaterials, and AI, analyzing their potential impact on surgical accuracy and tissue regeneration, while questioning if these advances represent a true revolution in healthcare or just incremental improvements.
View Article and Find Full Text PDF

Surgical resection is essential for treating solid tumors, with success largely dependent on the complete excision of neoplastic cells. However, neurosurgical procedures must delicately balance tumor removal with the preservation of surrounding tissue. Achieving clear margins is particularly challenging in cases like glioblastoma due to the limitations of traditional white light visualization.

View Article and Find Full Text PDF

Background- Postoperative delirium is a common complication associated with the elderly, causing increased morbidity and prolonged hospital stay. However, its risk factors in chronic subdural hematoma patients have not been well studied. Methods- A total of 202 consecutive patients with chronic subdural hematoma at Peking University Third Hospital between January 2018 and January 2023 were enrolled.

View Article and Find Full Text PDF

In tumor therapeutics, the transition from conventional cytotoxic drugs to targeted molecular therapies, such as those targeting receptor tyrosine kinases, has been pivotal. Despite this progress, the clinical outcomes have remained modest, with glioblastoma patients' median survival stagnating at less than 15 months. This underscores the urgent need for more specialized treatment strategies.

View Article and Find Full Text PDF