Sentinel Node Biopsy in Special Histologic Types of Invasive Breast Cancer.

Objective: To assess the feasibility of sentinel node biopsy (SNB) in ductal and lobular invasive breast cancer, a group of tumors known as special histologic type (SHT) of breast cancer.

Materials And Methods: Between January 1997 and July 2008, 2253 patients from 6 affiliated hospitals underwent SNB who had early breast cancer and clinically negative axilla. The patients' data were collected in a multicenter database.

[En garde, sentinel node!].

Injection technique and radiocolloid size are two critical parameters that must be carefully selected according to patient presentation and lesion appearance for accurate sentinel node detection in breast cancer. Scintigraphic detection and intraoperative localization are dependent on these parameters. The present clinical case illustrates how much deep intralesional tracer injection bears on our capacity to detect extra-axillary sentinel nodes and how the use of smaller-size radiocolloids may sometimes facilitate sentinel node detection.

[Radioisotopic localization of the sentinel lymph node in breast cancer. Preliminary results].

The aim of this preliminary work is to show the results of the radioisotopic localization of the sentinel node in breast cancer and the surgical resection using a gamma probe. We studied 10 patients with breast cancer without primary chemotherapy and 3 patients with primary chemotherapy before surgery. A lymphoscintigraphy was made after injection of 111 MBq of Tc99m-nanocolloid in a volume of 3 ml.