Background: Neuroblastoma often begins in infancy and one of the most common types of cancer among children is someone. Napabucasin (NP) (BBI608), a natural naphthoquinone emerging as a novel inhibitor of STAT3, has been found to effectively kill cancer stem-like tumor cells. On the other hand, the effect of Napabucasin on SH-SY5Y cells is currently unclear.
View Article and Find Full Text PDFPurpose: We aimed to investigate the role of gallic acid treatment on spinal cord tissues after spinal cord injury (SCI) and its relationship with endoplasmic reticulum (ER) stress by histochemical, immunohistochemical, and in-silico techniques.
Methods: Thirty female Wistar albino rats were divided into three groups: sham, SCI, and SCI+gallic acid. SCI was induced by dropping a 15-g weight onto the exposed T10-T11 spinal cord segment.
Ovarian cancer has the highest mortality rate in the world. Treatment methods are listed as surgery, chemotherapy, and radiotherapy, depending on the stage of cancer, but developing resistance to chemotherapy increases the need for alternative agents that act on the same pathways. The effects of rosmarinic acid (RA) and doxorubicin (DX) on the activation of FOXP3, an important tumor suppressor gene, in OVCAR3 cells were examined.
View Article and Find Full Text PDFAims: This study aims to evaluate the reliability and validity of the Community Balance and Mobility Scale (CB&M) in people with multiple sclerosis (PwMS).
Methods: A total of 65 PwMS (Expanded Disability Status Scale (EDSS) ≤ 5.5) were included in the study.
J Aging Stud
December 2024
This article aims to demonstrate a concrete example of how to apply an intersectional life course perspective into the study of ageing migrant women. The empirical material is based on a qualitative in-depth interview study conducted with 20 Turkish-born women who have migrated to Sweden in their early to mid-adulthood years. Despite increasing urgings from gerontologists to include intersectionality in studies on migrants, research often neglects how age, gender, and migration status interact, failing to recognise the diverse experiences of racialised older migrants.
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