Performance Optimization of a Large Geometry High Resolution-Secondary Ion Mass Spectrometer (HR-SIMS) for High Precision Measurements of Oxygen Isotopic Composition (δO) and U-Pb Geochronology in Zircon.

A large geometry high resolution secondary ion mass spectrometer (HR-SIMS) has been established as a part of the National Geochronology Facility (NGF) at Inter-University Accelerator Centre (IUAC), New Delhi. The performance of the instrument related to high spatial resolution, high mass resolving power (MRP), sensitivity of the instrument to measure low abundant isotopes, and sensitivity of the instrument for Pb signal under different conditions are optimized and presented in this paper. We report the precision of the order of ~ 0.

A Comprehensive Overview of Postbiotics with a Special Focus on Discovery Techniques and Clinical Applications.

The increasing interest in postbiotics, a term gaining recognition alongside probiotics and prebiotics, aligns with a growing number of clinical trials demonstrating positive outcomes for specific conditions. Postbiotics present several advantages, including safety, extended shelf life, ease of administration, absence of risk, and patentability, making them more appealing than probiotics alone. This review covers various aspects, starting with an introduction, terminology, classification of postbiotics, and brief mechanisms of action.

Geospatial AI solution to monitor and mitigate increasing adverse ecological and hydrological impacts of climate change in Uttarakhand Himalaya (India).

Though climate change and its adverse ecological and geohydrological impacts are being experienced across the world in all types of ecosystems but as far as the Himalaya mountain ecosystem is concerned, the rate of climate change and subsequent impacts have reached an alarming stage due to anthropogenic and technogenic intervention on natural process and now need most effective and less time taking management strategy. Addressing this burning environmental problem, a geospatial artificial intelligence (GeoAI) technique-based case study is presented here from one of the most densely populated and urbanized regions of Himalaya mountain, viz Uttarakhand Himalaya, which is also called central Himalaya. The results of the study suggest that due to quite a high rate of climate change, the climatic zones shifting towards higher altitudes at the average rate of 5.