Publications by authors named "M Ravindran"

Article Synopsis
  • * Researchers used community input, conducted focus groups, and gathered feedback from experts to develop a 91-item tool.
  • * The final measure will help understand the impacts of food allergies on families with children aged two to twelve years, emphasizing the importance of caregiver perspectives.
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Amyotrophic Lateral Sclerosis (ALS) is a severe neurodegenerative disorder marked by the gradual loss of motor neurons, leading to significant disability and eventual death. Despite ongoing research, there are still limited treatment options, underscoring the need for a deeper understanding of the disease's complex mechanisms and the identification of new therapeutic targets. This review provides a thorough examination of ALS, covering its epidemiology, pathology, and clinical features.

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Article Synopsis
  • Peanut allergy treatment options are currently limited, but new methods like epicutaneous immunotherapy (EPIT) are being explored.
  • Viaskin™ Peanut, a late-stage EPIT method, uses a patch that allows the skin to absorb allergens without breaking the skin barrier, aiming to build tolerance.
  • Clinical studies show that Viaskin Peanut can help desensitize children with peanut allergies while maintaining a good safety profile, with mild reactions that tend to lessen over time.
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Article Synopsis
  • The study investigates the use of botulinum toxin A (BTX-A) in treating acute acquired comitant esotropia (AACE) in children and young adults, particularly related to increased screen time during the COVID-19 pandemic.
  • Researchers analyzed data from 27 patients who received BTX-A injections to correct misalignment of the eyes caused by excessive use of devices like laptops and smartphones, focusing on the changes in eye deviation and binocular vision post-treatment.
  • Results indicated that BTX-A was effective, with significant improvements in eye alignment and visual function noted, especially when treatment was administered early after symptom onset.
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Article Synopsis
  • The study examines the difficulties faced in managing persistent graft rejections in a patient with Macular Corneal Dystrophy (MCD) who had Penetrating Keratoplasty (PKP) surgeries and also suffers from CREST syndrome, a form of systemic sclerosis.
  • A 47-year-old female patient underwent multiple surgical procedures and treatments over 13 years, which included both surgical interventions and immunosuppressive therapy, yet faced numerous graft failures and a significant decrease in vision.
  • The findings emphasize the detrimental effects of systemic autoimmune disorders on surgical outcomes, suggesting a need for careful systemic assessments and potentially stronger immunosuppressive approaches to improve graft survival in similar cases.
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