Purpose: Head and neck cancers (HNCs) are in general treated with conventional fractionation regimen of 1.8-2 Gy per fraction. Altered fractionation (ALFT) strategies such as hypofractionation radiotherapy (HYPO-RT), accelerated fractionation radiotherapy (AFRT), and hyperfractionation radiotherapy (HFRT) have not been practiced uniformly across centers in different parts of the world.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
March 2025
Therapeutic applications involving mesenchymal stem cells (MSCs) encounter challenges of attaining therapeutically potent and scaled up number during in-vitro batch culture. Recently, photobiomodulation (PBM) has emerged as a non-pharmacological method for enhancing MSC number, potency, and secretome production. However, the absence of a versatile, non-invasive technique to accurately identify PBM-induced biochemical alterations hinders the clinical translation of the approach.
View Article and Find Full Text PDFBackground The hypothalamic-pituitary-adrenal (HPA) axis and the hypothalamic-pituitary-thyroid (HPT) axis are two neuroendocrine systems that play a crucial role in maintaining homeostasis and regulating mood alterations. These axes have also been implicated in the development and progression of unipolar depression (UD). This study aims to investigate the role of serum cortisol and thyroid function tests on the severity of depression among patients with UD attending the psychiatry department.
View Article and Find Full Text PDFBackground: Chemical fortification and dose supplementation of vitamin B are widely implemented to combat deficiency symptoms. However, in situ, fortification of vitamin B in food matrixes can be a promising alternative to chemical fortification. The present study aimed to produce vitamin B-rich, probiotic guava juice fermented with Levilactobacillus brevis strain KU15152.
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