Publications by authors named "M Rasit Guney"
: Patients with reduced left ventricular ejection fraction (LVEF) are reported to have unfavorable outcomes following transcatheter aortic valve implantation (TAVI). This study aims to evaluate outcomes and identify predictive factors for LVEF recovery following TAVI in patients with reduced LVEF. : This retrospective study analyzed 114 patients with symptomatic severe aortic stenosis (AS) with LVEF < 40% who underwent TAVI between 2011 and 2023 at two centers.
View Article and Find Full Text PDF: Mitral regurgitation (MR) is a common condition observed in patients undergoing transcatheter aortic valve implantation (TAVI) for the treatment of aortic stenosis (AS). However, the impact of TAVI on MR outcomes and the factors predicting MR improvement remains uncertain. Understanding these predictors can enhance patient management and guide clinical decisions.
View Article and Find Full Text PDFBackground: The closure of a patent foramen ovale (PFO) using transseptal puncture has particular advantages and disadvantages. Thus, transseptal puncture should be re-evaluated in detail.
Aims: We aimed to assess the effectiveness of the detailed transseptal puncture technique in patients who underwent PFO closure due to cryptogenic stroke or transient ischemic attack in terms of residual shunts and atrial fibrillation.
Introduction: There are few data on permanent pacemaker implantation (PPMI) in patients who have undergone transcatheter aortic valve implantation (TAVI) for bicuspid aortic valve (BAV) stenosis.
Aim: The purpose of this study was to evaluate the predictors and incidence of PPMI in bicuspid patients using a balloon-expandable (BE) TAVI device.
Material And Methods: A total of 62 patients with bicuspid morphology who had undergone successful TAVI using a BE device without previous PPMI were included (retrospectively).
Article Synopsis
- Prostate cancer (PCa) has an immunosuppressive environment that limits immune activation, resulting in reduced activity of cytotoxic T-cells and increased levels of regulatory T cells (Tregs) and tumor-associated macrophages (TAMs), which are linked to poorer outcomes.
- The review emphasizes the role of different immune cells, including beneficial Th1 and harmful Th17 cells, in influencing tumor behavior, and how PCa's low immunogenicity poses challenges for immunotherapy.
- Chemotherapy is shown to have the potential to enhance the immune response against tumors by transforming the "cold" tumor microenvironment into a "hot" one, improving treatment efficacy by targeting immunosuppressive cells.