Publications by authors named "M Rashmi"
The squash species has been historically utilized by both animals and humans as a food source. It is an annual dicotyledonous vegetable known for its health benefits, including reducing the risk of various diseases, such as cancer, high blood pressure, diabetes, intestinal disorders, and atherosclerosis, in humans. However, the cultivation of this valuable crop is often challenged by diseases such as powdery mildew (PM), caused by the fungus .
View Article and Find Full Text PDFDrug discovery is a complex and multifaceted process aimed at identifying new therapeutic compounds with the potential to treat various diseases. Traditional methods of drug discovery are often time-consuming, expensive, and characterized by low success rates. Because of this, there is an urgent need to improve the drug development process using new technologies.
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- The study evaluated the effects of CRD7 on performance and gut health in Swiss albino mice, showing that both non-encapsulated and electrohydrodyanamically encapsulated CRD7 increased body weight and feed intake over four weeks.
- Supplementation with CRD7 enhanced gut barrier functions by increasing tight junction proteins, reducing inflammation, and promoting beneficial short-chain fatty acids, while causing no adverse effects in liver and intestinal tissues.
- The encapsulated form of CRD7 effectively improved gut microbiota by increasing beneficial bacteria and reducing harmful ones, suggesting its potential use in food and feed formulations to support gut health and address related diseases.
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- The study evaluated the effectiveness of calcium hydroxide and triple antibiotic paste in treating apical periodontitis, a common tooth-related inflammation.
- A total of 304 teeth from 215 patients were analyzed, with participants divided into three groups: calcium hydroxide, triple antibiotic paste, and a control group.
- Over 12 months, both medicaments significantly improved healing and reduced inflammation, with calcium hydroxide showing the best results in terms of healing presence and clinical parameters.
Article Synopsis
- The cell wall of soybeans faces damage from polygalacturonases (PGs) produced by fungi, leading to disease and loss of quality.
- Soybeans possess a resistance protein called polygalacturonases-inhibiting proteins (PGIPs) that bind to PGs, with specific mutations in PGIPs influencing their effectiveness against fungal infections.
- Research using docking and molecular dynamics simulations reveals the structural interactions between gmPGIP and ssPG, providing insights for engineering soybean varieties that are more resistant to fungal attacks, potentially increasing crop yields.