Publications by authors named "M Rasche"

Article Synopsis
  • * Three new recurring KMT2A-rearranged groups were identified, and a significant variation in 5-year event-free survival rates was observed across 13 different groups, highlighting the impact of genetic factors on patient outcomes.
  • * The research suggests incorporating five specific adverse-risk KMT2A fusions into current risk stratification models and calls for further studies to confirm the associations
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Vaccination against SARS-CoV-2 with coronavirus vaccines that elicit protective immune responses is critical to the prevention of severe disease and mortality associated with SARS-CoV-2 infection. Understanding the adaptive immune responses to SARS-CoV-2 infection and/or vaccination will continue to aid in the development of next-generation vaccines. Studies have shown the important role of SARS-CoV-2-specific antibodies for both disease resolution and prevention of COVID-19 serious sequelae following vaccination.

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Article Synopsis
  • SARS-CoV-2 remains a significant global health threat, highlighting the need for in-depth studies on COVID-19 immunity due to declining antibody responses and the emergence of new variants.
  • * The study emphasizes the importance of T-cell-mediated cellular immunity for long-lasting protection against the virus, which is more durable and versatile compared to antibody responses.
  • * A procedure using the ELISPOT assay is presented to assess T-cell responses in human blood samples post-infection or vaccination, which can also be adapted for research on other viral pathogens.
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Background: Pediatric Post-COVID-Condition (PPCC) clinics treat children despite limited scientific substantiation. By exploring real-life management of children diagnosed with PPCC, the International Post-COVID-Condition in Children Collaboration (IP4C) aimed to provide guidance for future PPCC care.

Methods: We performed a cross-sectional international, multicenter study on used PPCC definitions; the organization of PPCC care programs and patients characteristics.

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The microparticle quality and reproducibility of Li(NiCoMn)O (NCM811) cathode materials are important for Li-ion battery performance but can be challenging to control directly from synthesis. Here, a scalable reproducible synthesis process is designed based on slug flow to rapidly generate uniform micron-size spherical-shape NCM oxalate precursor microparticles at 25-34 °C. The whole process takes only 10 min, from solution mixing to precursor microparticle generation, without needing aging that typically takes hours.

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