Unveiling the emerging concern of per- and polyfluoroalkyl substances (PFAS) and their potential impacts on estuarine ecosystems.

Per- and polyfluoroalkyl substances (PFAS) have become ubiquitous chemicals that pose potentially serious threats to both human health and the integrity of the ecosystem. This review compiles current knowledge on PFAS contamination in estuaries, focusing on sources, abundance, distribution, fate, and toxic mechanisms. It also addresses the health risks associated with these compounds and identifies research gaps, offering recommendations for future studies.

A Comprehensive Analysis of Surgical Outcomes for Spinal Fractures in Patients With Ankylosing Spondylitis: A 13-Year Prospective Study.

Introduction: Ankylosing spondylitis (AS), a chronic inflammatory spondyloarthropathy affecting the spine, progressively leads to increased spinal stiffness. This condition increases the risk of spine fractures in patients, even from trivial injuries. The process of slow bone formation within the ligaments of the spine and the fusion of the spinal diarthrosis contribute to the most prominent symptom of progressive stiffness of joints, predominantly affecting the spine and sacroiliac joints.

Histological Changes of the Mucosal Epithelium in the Chicken Intestine during Pre- and Post-Hatching Stages.

This study clarified the histological changes in the mucosal epithelium of the chicken intestine during the pre- and post-hatching stages. The duodenum, jejunum, ileum, and colorectum were collected from embryos at 15, 17, 18, 19, and 21 days of incubation and from chicks at 1 and 3 days after hatching. Paraffin sections prepared from tissue samples were stained with periodic acid-Schiff followed by alcian blue for histological analysis and to detect goblet cells.

Dermatofibrosarcoma Protuberans, Version 1.2025, NCCN Clinical Practice Guidelines In Oncology.

Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous soft tissue sarcoma and affects an estimated 1,500 people annually in the United States. DFSP frequently exhibits extensive local infiltration. Initial treatment is through surgical excision, and care should be taken to ensure that negative margins are achieved to minimize recurrence.