Publications by authors named "M Rajappa"
Background Chronic kidney disease (CKD) leads to a progressive decline in renal function, primarily due to deteriorating kidney structures. Vascular calcification is a key effect of CKD. MicroRNAs (miRNAs) play a significant role in the onset and progression of both cardiovascular illness and CKD.
View Article and Find Full Text PDFBackground: Chronic kidney disease (CKD) is defined by gradual deterioration of renal parenchyma and decline of functioning nephrons. The risk of cardiovascular events is drastically increased in patients with CKD. This complicated link of CKD and cardiovascular disease (CVD) is not well understood till date.
View Article and Find Full Text PDFDefect detection in pharmaceutical blister packages is the most challenging task to get an accurate result in detecting defects that arise in tablets while manufacturing. Conventional defect detection methods include human intervention to check the quality of tablets within the blister packages, which is inefficient, time-consuming, and increases labor costs. To mitigate this issue, the YOLO family is primarily used in many industries for real-time defect detection in continuous production.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates factors contributing to acute kidney injury (AKI) during cardiac surgery, focusing on the difference in mean arterial pressure (MAP) before and during the procedure, as well as the role of plasma Neutrophil gelatinase-associated lipocalin (NGAL).
- Conducted on 112 high-risk patients undergoing heart surgery, the research measured delta MAP and NGAL levels to find correlations with postoperative AKI occurrences using the KDIGO classification.
- Results showed that a delta MAP greater than 25.67 mmHg was predictive of AKI, while serum NGAL levels were more strongly associated with early AKI, suggesting its potential as a biomarker for risk assessment after cardiac surgery.
Objectives: Synaptic plasticity markers are known to alter in schizophrenia. The objective of the study was to investigate the genotype and allele frequency of neurotrophin-3 (NT-3) gene polymorphism (rs6489630, rs6332, and rs11063714) and plasma NT-3 levels in schizophrenia and their relation with cognitive status.
Materials And Methods: The study was conducted on 216 Schizophrenia patients and 216 controls.