Publications by authors named "M Rainfray"

Background: The prognostic assessment of older cancer patients is complicated by their heterogeneity. We aimed to assess the prognostic value of routine inflammatory biomarkers.

Methods: A pooled analysis of prospective multicenter cohorts of cancer patients aged ≥70 was performed.

View Article and Find Full Text PDF

Context: The role of comprehensive geriatric assessment for older patients with advanced chronic kidney disease still needs to be defined. In this population, data is lacking on the care proposals made by geriatricians during comprehensive geriatric assessment and on the follow-up of these proposals.

Objectives: To describe a population of older outpatients with advanced renal disease seen at a geriatric consultation, and geriatric syndromes identified.

View Article and Find Full Text PDF

Background: The absence of fever in bacteremia in patients who are older is known to delay diagnosis. Our objective was to determine whether atypical presentation was associated to mortality as a result of bacteremia in this patient cohort as well as possible factors associated with this atypical presentation.

Methods: We conducted an observational prospective study in 2 French university hospitals in 2016-2017 including patients ages ≥75 years with bacteremia.

View Article and Find Full Text PDF

Recent research suggests that sleep disorders or changes in sleep stages or EEG waveform precede over time the onset of the clinical signs of pathological cognitive impairment (e.g., Alzheimer's disease).

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the factors that contribute to functional decline in older cancer patients, focusing on a population-based sample rather than just hospital cases.
  • Researchers analyzed data from cancer registries to examine how various demographic, health-related, and cancer-specific variables influenced functional status before and after cancer diagnosis.
  • Key findings revealed that older age (especially 85+), cognitive impairment, advanced cancer stage, low education, and polypharmacy were significant predictors of limitations in daily living activities among these patients, highlighting the need for targeted clinical assessments.
View Article and Find Full Text PDF