Publications by authors named "M Ragunath"

Post-transcriptional modifications (PTMs) are pivotal in the regulation of gene expression, and pseudouridylation is emerging as a critical player. This modification, facilitated by enzymes such as NOB1 (PNO1), is integral to ribosome biogenesis. PNO1, in collaboration with the NIN1/RPN12 binding protein 1 homolog (NOB1), is vital for the maturation of ribosomes, transitioning 20S pre-rRNA into functional 18S rRNA.

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Developing non-noble, earth-ample, and stable electrocatalysts are highly anticipated in oxygen-evolution reaction (OER) and hydrogen-evolution reaction (HER) at unique pH conditions. Herein, we have synthesized bimetallic (nickel and iron) zeolite imidazolate framework (ZIF)-based nanofibrous materials via a simple electrospinning (ES) process. The structural stability of the fibrous material is subjected to various calcination conditions.

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Out of various available methods, generation of hydrogen by electrocatalytic water splitting is the most accepted one which consists of two half-cell reactions, , oxygen evolution reaction (OER) at the anode and hydrogen evolution reaction at the cathode. OER is a complex four-electron transfer process, and to sustain the spontaneous generation of hydrogen at the cathode, it is urgent to develop some earth-abundant, low-cost electrode materials. Recently, use of cobalt-based hydroxide as the electrode substrate has taken much consideration and has been fabricated over various substrates.

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Article Synopsis
  • The study focuses on the impact of the ANXA5 M2 haplotype, a potential procoagulant biomarker, on pregnancy outcomes in couples undergoing IVF and evaluates the effectiveness of testing and treating with low molecular weight heparin (LMWH).
  • Involving 103 IVF couples with the ANXA5 M2 haplotype, the study compares their live birth rates to 1000 unscreened couples, finding that ANXA5 M2 carriers had similar live birth rates to both the fertile comparison group and matched controls.
  • Results showed that treated male carrier couples had a higher live birth incidence compared to female carrier couples, suggesting that the management protocol for treating ANXA5 M2 positive
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