Publications by authors named "M Rafael"
The global HIV epidemic remains a major public health challenge, with DTG playing a key role in ART regimens due to its efficacy and tolerability. This study evaluated virological outcomes and resistance mutations in patients on DTG in Mozambique through a retrospective cohort study in seven DREAM centers. Data from 29,601 patients (98.
View Article and Find Full Text PDFVaccines are the most effective and sustainable intervention to control ticks and tick-borne diseases (TBD). Using a personalized vaccine design based on regional tick genotypes, a Rhipicephalus appendiculatus Subolesin protective antigen was used in a field trial evaluating tick vaccine efficacy, effectiveness, and safety in cattle infested with multiple tick species in different Ugandan agro-ecological zones. Vaccination with SUB was safe with a protective capacity against anemia and infection, and reduced the number of infested cattle, tick fitness (feeding and reproduction) with vaccine effectiveness against multiple tick species between 93.
View Article and Find Full Text PDFTraining Public Health Nurses on Disaster Shelter Care Using a Flipped Classroom Approach.
Disaster Med Public Health Prep
September 2024
Objective: With the increase in natural disasters and the expected role of public health nurses (PHNs) in responding, it is crucial to develop evidence-based disaster preparedness and management training programs tailored to the needs of PHNs. This study evaluates the effectiveness of a flipped classroom approach in disaster training for PHNs.
Methods: A total of 42 PHNs completed a 5-hour online training program and an in-person 8-hour training session at a local nursing school.
Article Synopsis
- Different mosquito species show varying resistance levels to synthetic insecticides like temephos, sparking interest in alternative insecticides such as semi-synthetic dillapiole butyl ether.
- Dillapiole butyl ether has shown effective ovicidal and larvicidal properties without significant risks of mutagenicity or cytotoxicity for humans and other vertebrates in drinking water.
- Testing on Balb/C mice indicated that dillapiole butyl ether only induced genetic damage at high concentrations (40 mg/kg), suggesting lower concentrations (10 and 20 mg/kg) could be safe and effective for mosquito control.
Introduction: The outbreak of coronavirus disease 2019 (COVID-19) had affected clinical practice in several ways, including the restriction of nonessential endoscopic procedures. Therefore, our aim was to evaluate how colorectal cancer (CRC) diagnosis and management was affected during the first year of pandemics in Portugal.
Methods: This is a Portuguese substudy of the French retrospective multicentric study ETICC ().