Smoking significantly increases resistin concentrations in perivascular adipose tissue (PVAT) among coronary artery disease (CAD) patients, with ever-smokers showing notably higher levels than never-smokers.
The study involved 110 CAD patients scheduled for coronary artery bypass grafting (CABG), categorized by smoking status (never, current, and past smokers), with resistin and inflammatory markers measured.
Findings indicate a strong correlation between smoking history (pack-years), plasma resistin, and inflammatory markers (IL-6, hs-CRP), highlighting the negative impact of smoking on endothelial function and fat tissue biology in CAD patients.
- The study investigates the potential of heart rate (HR) recovery after exercise as a predictor of functional improvement in patients with severe aortic stenosis undergoing aortic valve surgery (TAVI).
- Conducting a 6-minute walk test (6MWT) before and three months after TAVI on 93 patients showed that the change in walking distance can be linked to HR recovery patterns.
- The findings indicate that measuring HR recovery, especially after 2 minutes, could effectively assess exercise capacity improvements post-surgery and help identify patients who may not benefit significantly from the procedure.