Publications by authors named "M R Wills"

It is important to be able to retrospectively determine severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections with high accuracy, both for post-coronavirus disease 2019 (COVID-19) epidemiological studies, and to distinguish between Long COVID and other multi-syndromic diseases that have overlapping symptoms. Although serum antibody levels can be measured to retrospectively diagnose SARS-CoV-2 infections, peptide stimulation of memory T cell responses is a more sensitive approach. This is because robust memory T cells are generated after SARS-CoV-2 infection and persist even after antibodies wane below detectability thresholds.

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Article Synopsis
  • Obesity significantly increases the risk of idiopathic intracranial hypertension (IIH), and this study investigates how bariatric surgery impacts clinical outcomes for patients with both conditions.
  • The study analyzed data from 97 predominantly female patients (median age 46.7) who underwent various types of bariatric surgery, leading to a median weight loss of 24% and notable improvements in IIH symptoms, including headaches and visual issues.
  • Results showed a significant reduction in mean lumbar opening pressure and a decrease in the usage of medications for IIH post-surgery, indicating that bariatric surgery can effectively alleviate IIH symptoms in obese patients.
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