Mechanistic aspects of the formation of aldehydes and nitriles in photosensitized reactions of aldoxime ethers.

The photooxidation of a series of aldoxime ethers was studied by laser flash photolysis and steady-state (product studies) methods. Nanosecond laser flash photolysis studies have shown that chloranil (CA)-sensitized reactions of the O-methyl (1), O-ethyl (2), O-benzyl (3), and O-tert-butyl (4) benzaldehyde oximes result in the formation of the corresponding radical cations. In polar non-nucleophilic solvents such as acetonitrile, there are several follow-up pathways available depending on the structure of the aldoxime ether and the energetics of the reaction pathway.

Comparison of resting intracoronary particulate imaging and stress thallium-201 studies.

Stress thallium-201 and resting dual intracoronary particulate imaging were evaluated in 120 patients who underwent coronary angiography. Forty of 42 patients without significant coronary disease had normal stress images and 41 had normal rest studies. Eighty-three stress perfusion defects were identified in 61 of 78 patients with coronary artery disease.