Publications by authors named "M R Stephen"

Purpose: Psychological distress, including anxiety and depression, is common among adults with CF, associating with poor quality of life, lung function, and healthcare utilization. This 3-year, multi-site, telehealth-delivered randomized trial sought to determine whether Acceptance and Commitment Therapy (ACT with CF) is superior to supportive psychotherapy (SP), in improving psychological functioning for adults with CF.

Methods: One hundred twenty-four adults with CF and elevated anxiety and/or depressive symptoms were recruited coincident with the first COVID lockdown, from Thomas Jefferson University Hospitals, University of Virginia, Augusta University, Duke University Medical Center, and social media.

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  • * It occurs after age 30, and diagnosis is made through various eye examinations, including fundus photography and optical coherence tomography.
  • * Treatment options include laser therapy and injections to prevent complications like retinal detachment, but outcomes can vary, emphasizing the need for early detection and intervention.
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National public health emergency operations centers (PHEOCs) serve as hubs for coordinating information and resources for effective emergency management. In the a simulation exercise is 1 of 4 components that can be used to test the functionality of a country's emergency response capabilities in a simulated situation. To test the functionality of PHEOCs in World Health Organization African Region member states, a regional functional exercise simulating an Ebola virus disease outbreak was conducted.

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  • Recombinant porcine factor VIII (rpFVIII) is used to treat bleeding in patients with acquired hemophilia A.
  • A significant challenge in its effectiveness is the presence of cross-reacting anti-human FVIII antibodies in patients.
  • In this study, 52% of patients with acquired hemophilia A had these antibodies, which resulted in lower FVIII activity levels after receiving rpFVIII.
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