Publications by authors named "M R Siebert"

Background: The variability in patients' risk of oral mucositis (OM) has been, in part, attributed to differences in host genomics. The aim better define the role of genomics as an OM risk by investigating the association between genetic variants and the presence and severity of OM in pediatric patients with osteosarcoma (OS) undergoing chemotherapy (CT).

Methods: A longitudinal observational retrospective study was conducted.

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Article Synopsis
  • Polycyclic aromatic hydrocarbons (PAHs) are complex organic molecules with multiple interconnected aromatic rings, commonly found in space.
  • Researchers discovered 1-cyanopyrene, a specific type of PAH derived from pyrene, in the dense cloud TMC-1 using the Green Bank Telescope.
  • The findings imply that PAHs, particularly pyrene, play a significant role in contributing carbon to young planetary systems, suggesting they originate from cold molecular clouds.
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Purpose: To evaluate the shear bond strength (SBS) of resin composite to dentin contaminated with artificial saliva (AS) containing mucin and amylase using an experimental method controlling the volume of saliva and adhesive in a defined surface area.

Methods: Flat bonding surfaces were prepared on extracted human molars (320 grit surface). Using adhesive tape, a 4.

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Background: Missed opportunities to reduce numbers of primary major lower-limb amputation and increase limb-salvage procedures when treating chronic limb-threatening ischaemia have previously been identified in the literature. However, the potential economic savings for healthcare providers when salvaging a chronic limb-threatening ischaemia-affected limb have not been well documented.

Methods: A model using National Health Service healthcare usage and cost data for 1.

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Background: Wound healing is a multistep process involving coordinated responses of a variety of cell types, cytokines, growth factors, and extracellular matrix (ECM) components leading to the physiological restoration of tissue integrity. Photobiomodulation therapy (PBMT) has been highlighted as an approach to improve the healing process, nonetheless at the molecular level, the effects of PBMT are not entirely understood.

Aim: To systematically review publications that investigated gene expression after PBMT during in vivo skin repair.

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