Publications by authors named "M R Rose"
Air pollution is associated with increased risk of neurodegenerative and neuropsychiatric conditions. While animal models have increased our understanding of how air pollution contributes to brain pathologies - including through oxidative stress, inflammatory, and stress hormone pathways - investigation of underlying mechanisms remains limited due to a lack of human-relevant models that incorporate systemic processes. Our objective was to establish an ex vivo approach that enables assessment of the roles of plasma mediators in pollutant-induced effects in the brain.
View Article and Find Full Text PDFRecent successes in the identification of biomarkers and therapeutic targets for diagnosing and managing neurological diseases underscore the critical need for cutting-edge biobanks in the conduct of high-caliber translational neuroscience research. Biobanks dedicated to neurological disorders are particularly timely, given the increasing prevalence of neurological disability among the rising aging population. Translational research focusing on disorders of the central nervous system (CNS) poses distinct challenges due to the limited accessibility of CNS tissue pre-mortem.
View Article and Find Full Text PDFProblem: It is unknown whether the deployment of registered nurses to assist midwives in the provision of postnatal care eases the burden of workforce shortages.
Background: The largest public maternity health service in Western Australia began employing registered nurses in 2022 to assist midwives with the provision of postnatal care on maternity wards in response to staffing shortages, exacerbated by COVID-19.
Aim: To explore midwives' and registered nurses' experiences of providing postnatal care on maternity wards together.
Article Synopsis
- The ICU environment exposes patients, relatives, and staff to traumatic experiences, prompting the need for effective mental health support to mitigate adverse effects.
- Current mental health services in healthcare systems typically react to existing conditions, making them less effective for prevention; integrated psychosocial support (IPS) models show promise by incorporating psychologists directly into ICU teams.
- Psychologists in the ICU can identify and address mental health issues early, enhancing support for patients and staff, and improving the overall resilience of the ICU team.
Objectives: This study aimed to compared Patient-Reported Outcomes Measurement Information System (PROMIS) anxiety, depression, and anger item bank among Korean, US and Dutch general population.
Methods: Between December 2021 and January 2022, we surveyed representative Korean participants (N = 2699). Then we compared the mean T-scores of PROMIS anxiety, depression, and anger full items bank among Korean, US (N = 1696) and the Dutch (N = 1002) populations.