Publications by authors named "M R Neff"

Background: Maternal mental health is vital to overall well-being, particularly among expectant and postpartum Black and Latina women who experience higher stress levels and mental health challenges. Traditional healthcare systems often fail to meet these needs, underscoring the need for innovative and accessible interventions. NurtureVR, a digital maternal mental health and educational program, leverages virtual reality to offer mindfulness, relaxation, and guided imagery to support these women.

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Article Synopsis
  • Researchers have developed a straightforward method to isolate T-DNA-free mutants after gene editing in plants using CRISPR-Cas9, streamlining the process and removing the need for complex outcrossing techniques.
  • This technique utilizes Basta-sensitive seedlings that can be rescued by transplanting them to Basta-free media, allowing for the identification of plants without the Cas9 T-DNA insert.
  • The study also found varying recovery rates in different crops, with wheat showing the highest success in recovering from Basta selection, indicating the potential for broad application across various plant species.
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Background: General practitioners play a unique key role in diagnosing patients with unclear diseases. Decision support systems in primary care can assist with diagnosis provided that they are efficient and user-friendly.

Objectives: The objective of this study is to develop a high-fidelity prototype of the user interface of a clinical decision support system for primary care, particularly for diagnosis support in unclear diseases, using expert inspections at an early stage of development to ensure a high level of usability.

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Translation initiation is a highly regulated step needed for protein synthesis. Most cell-based mechanistic work on translation initiation has been done using non-stressed cells growing in medium with sufficient nutrients and oxygen. This has yielded our current understanding of 'canonical' translation initiation, involving recognition of the mRNA cap by eIF4E1 followed by successive recruitment of initiation factors and the ribosome.

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Background: Hospital-acquired complications add to patient morbidity and mortality, costs, length of stay, and negative patient experience. Patient Safety Indicators (PSIs) are a validated and widely used metric to evaluate hospital administrative data on preventing these events. Although many studies have addressed PSI validity, few have aimed to reduce PSI through clinical care.

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