Publications by authors named "M R Nasca"

Rosacea diagnosis and treatment in children are challenging, due to its rarity and to the lack of approved pharmacological agents for its treatment in this age group. In this case series, response to treatment with once daily applications of ivermectin (IVM) 1% cream for 12 weeks in 10 children affected by mild to severe inflammatory rosacea was evaluated clinically by Investigator Erythema Severity Assessment (IESA), Investigator Global Assessment of Severity (IGA-S), Investigator Global Assessment score of Global Efficacy (IGA-GE), and instrumentally by dermoscopy and Erythema-Directed Digital Photography (EDDP). Clinical improvement was achieved at the end of treatment compared to baseline (IESA: 2.

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Article Synopsis
  • Antibiotic resistance is a growing global issue, affecting both systemic and topical treatments for infections, highlighting the need for alternatives like antiseptics.
  • Polyhexanide (PHMB) is noted for its effectiveness in controlling infections without promoting resistance, making it a viable option for treating various dermatological conditions.
  • The text suggests updated clinical practices for managing wounds and skin infections, advocating for the use of innovative treatments like PHMB and Rigenase® instead of traditional topical antibiotics.
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Article Synopsis
  • Scalp rosacea is frequently misdiagnosed and lacks approved treatments, making it a challenge for healthcare professionals.
  • A case study of 5 adults with scalp rosacea showed positive results using ivermectin 1% cream applied daily for 12 weeks.
  • The findings indicate that assessing the scalp during rosacea evaluations is important and suggest that ivermectin may be an effective treatment option for scalp rosacea.
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Article Synopsis
  • Infection at surgical sites is common after dermatologic procedures, but using antibiotics to prevent these infections is controversial due to rising antibiotic resistance, especially in Italy where misuse is rampant.* -
  • A survey distributed to dermatologists nationwide revealed that over 70% routinely use topical antibiotics post-procedure, despite growing evidence against their effectiveness in preventing infections.* -
  • The results indicate a significant misunderstanding about the role of antibiotics in wound care, highlighting the urgent need for education among healthcare professionals to combat the ongoing issue of antibiotic resistance.*
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