Hydrothermal sediments host phylogenetically diverse and physiologically complex microbial communities. Previous studies of microbial community structure in hydrothermal sediments have typically used short-read sequencing approaches. To improve on these approaches, we use LoopSeq, a high-throughput synthetic long-read sequencing method that has yielded promising results in analyses of microbial ecosystems, such as the human gut microbiome.
View Article and Find Full Text PDFPurpose: The purpose of this qualitative study is to demonstrate the use of patient-reported outcome measure-based journey maps in facilitating clinicians' ability to communicate with patients about their well-being at each phase of their cancer journey.
Methods: Individual semi-structured online and phone interviews were conducted with older adults in British Columbia, Canada. Participants (n = 6) were asked to describe their cancer experiences associated with their well-being score using the Edmonton Symptom Assessment System revised questionnaire throughout their cancer journey (i.
Objectives: To identify risk factors for progression to severe COVID-19 and estimate the odds of severe COVID-19 associated with vaccination among patients with systemic lupus erythematosus (SLE).
Methods: This retrospective cohort study identified adults with SLE in the Merative™ MarketScan Databases. Patients were continuously enrolled the year before 1 April 2020 (baseline) and had a COVID-19 diagnosis between 1 April 2020 and the earliest of death, enrolment end or 31 December 2021.
Introduction: This is a rapid review of the published evidence on the effectiveness of interventions for mitigating workplace violence against staff in hospital emergency departments. Focused on the specific needs of an urban emergency department in Canada, this project sought to address the question, "What interventions have evidence regarding effectiveness for addressing workplace patient/visitor violence toward staff in the emergency department?"
Methods: Following Cochrane Rapid Review methods, 5 electronic databases (MEDLINE via PubMed, Cochrane CENTRAL, Embase, PsycINFO, CINAHL) and Google Scholar were searched in April 2022 for intervention studies to reduce or mitigate workplace violence against staff in hospital emergency departments. Critical appraisal was conducted using Joanna Briggs Institute tools.