In the last few decades, non-occupational asbestos-related diseases have been documented in populations living near naturally occurring asbestos (NOA) sites, including regions in Greece, Cyprus, China, New Caledonia, Turkey, and Italy. This highlights the critical need to assess geological and environmental hazards associated with NOA. Fibrous antigorite, among the >400 naturally occurring fibrous minerals, has emerged as a potential health and environmental hazard.
View Article and Find Full Text PDFErionite is a ubiquitous natural zeolite, often occurring with fibrous habit, whose strong tumorigenic activity to humans has been certified by its inclusion in the Group 1 Human-Carcinogenic list by the International Agency for Research on Cancer. To date, the reason(s) of erionite toxicity are still unclear, albeit several hypotheses have been proposed. The present work, based on the combined analysis of the chemical and structural modifications of erionite fibres following incubation in human THP-1 macrophages and evaluation of cellular response, indicates that, upon macrophage phagocytosis, a large release of cations is counterbalanced by a significant sequestration of hydronium ions from lysosomes provoking a quick pH dysregulation.
View Article and Find Full Text PDFNanomaterials (Basel)
November 2023
Nowadays, the use of multi-functional mortars has increased significantly, with interesting applications in the sustainable construction. In the environment, the cement-based materials are subjected to leaching, so the assessment of potential adverse effects upon aquatic ecosystem is necessary. This study focuses on the evaluation of the ecotoxicological threat and of a new type of cement-based mortar (CPM-D) and its raw materials leachates.
View Article and Find Full Text PDF