Publications by authors named "M R Montereali"

In the last few decades, non-occupational asbestos-related diseases have been documented in populations living near naturally occurring asbestos (NOA) sites, including regions in Greece, Cyprus, China, New Caledonia, Turkey, and Italy. This highlights the critical need to assess geological and environmental hazards associated with NOA. Fibrous antigorite, among the >400 naturally occurring fibrous minerals, has emerged as a potential health and environmental hazard.

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Erionite is a ubiquitous natural zeolite, often occurring with fibrous habit, whose strong tumorigenic activity to humans has been certified by its inclusion in the Group 1 Human-Carcinogenic list by the International Agency for Research on Cancer. To date, the reason(s) of erionite toxicity are still unclear, albeit several hypotheses have been proposed. The present work, based on the combined analysis of the chemical and structural modifications of erionite fibres following incubation in human THP-1 macrophages and evaluation of cellular response, indicates that, upon macrophage phagocytosis, a large release of cations is counterbalanced by a significant sequestration of hydronium ions from lysosomes provoking a quick pH dysregulation.

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Article Synopsis
  • The study examines how amosite asbestos fibers dissolve when exposed to a synthetic solution that replicates body conditions, focusing on a specific pH and temperature over an extended period.
  • Researchers used various analytical methods to compare the dissolution behavior of amosite to other asbestos types (tremolite and crocidolite), finding similar incongruent dissolution patterns and a preferential release of magnesium and calcium ions.
  • Interestingly, no iron was detected as being released from amosite fibers, which suggests unique stability traits, and highlights the importance of understanding these chemical changes for assessing the long-term toxicity related to asbestos materials.
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Article Synopsis
  • The environmental impact of natural occurrences of asbestos (NOA) is a rising concern, but inconsistent sampling and analytical methods complicate the issue.
  • A multidisciplinary approach involving geology, chemistry, and toxicology is suggested to assess the hazards posed by NOA, specifically focusing on antigorite found in Varenna Valley, Italy.
  • Findings indicate that antigorite has a toxicity profile and bioactivity potentially comparable to chrysotile asbestos, highlighting the need for careful hazard assessment of NOA sites.
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Nowadays, the use of multi-functional mortars has increased significantly, with interesting applications in the sustainable construction. In the environment, the cement-based materials are subjected to leaching, so the assessment of potential adverse effects upon aquatic ecosystem is necessary. This study focuses on the evaluation of the ecotoxicological threat and of a new type of cement-based mortar (CPM-D) and its raw materials leachates.

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