Virginia Memory Project: Using the Healthy Brain Initiative Roadmap to design a statewide dementia registry.

Introduction: The Virginia Memory Project (VMP) is a statewide epidemiological registry for Alzheimer's disease and related disorders (ADRD) and other neurodegenerative conditions. It aims to support dementia research, policy, and care by leveraging the Centers for Disease Control (CDC) Healthy Brain Initiative (HBI) Roadmap.

Methods: To capture comprehensive data, the VMP integrates self-enrollment and automatic enrollment using Virginia's All-Payer Claims Database (APCD).

The Impact of Air Pollution on Cardiovascular Health Outcomes in African Populations: A Scoping Review.

Background: Air pollution is a significant environmental risk factor for cardiovascular diseases (CVDs), but its impact on African populations is under-researched due to limited air quality data and health studies.

Objectives: The purpose of this study was to synthesize available research on the effects of air pollution on CVDs outcomes in African populations, identify knowledge gaps, and suggest areas for research and policy intervention.

Methods: A systematic search of PubMed was conducted using terms capturing criteria ambient air pollutants (for example particulate matter, nitrogen dioxide, ozone, and sulfur dioxide) and CVDs and countries in Africa.

Balance Changes in Adult Cancer Survivors Participating in a 16-Week Therapeutic Yoga Program.

Introduction: Balance problems arising from cancer and its treatments can significantly impact daily functionality and quality of life. Improving balance as part of a cancer treatment plan could result in better patient outcomes. Thus, the aim of this study was to determine whether an integrative therapeutic yoga intervention can improve balance in a heterogenous population of cancer survivors (CS).

[C]MK-6884 PET imaging reveals lower M muscarinic acetylcholine receptor availability following cocaine self-administration in male rats.

Background: Cocaine Use Disorder (CUD) remains a significant problem in the United States, with high rates of relapse and no present FDA-approved treatment. The acetylcholine neurotransmitter system, specifically through modulation of muscarinic acetylcholine receptor (mAChR) function, has shown promise as a therapeutic target for multiple aspects of CUD. Enhancement of the M mAChR subtype via positive allosteric modulation has been shown to inhibit the behavioral and neurochemical effects of cocaine across several rodent models of CUD.

Sleep quality and duration as predictors of alcohol and cannabis use motives in daily life.

Objective: Alcohol and cannabis are two of the most widely used substances in the United States, where sleep problems are also prominent. Although poor sleep is linked to substance use, little is known about how prior-night sleep contributes to next-day decisions to use substances in daily life. This study tested the impact of prior-night sleep duration and quality on momentary motives for alcohol (Aim 1) and cannabis use (Aim 2).