Publications by authors named "M R McKenzie"

This pilot study evaluated the outcomes associated with a training workshop in cognitive-behavioural therapy with exposure and response prevention (ERP) for youth with obsessive-compulsive disorder (OCD) aimed at improving clinicians' capabilities and motivations. Questionnaires and role-plays were completed by 17 Australian clinicians working across community youth (i.e.

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To determine if a variant identified by diagnostic genetic testing is causal for disease, applied genetics professionals evaluate all available evidence to assign a clinical classification. Experimental assay data can provide strong functional evidence for or against pathogenicity in variant classification, but appears to be underutilised. We surveyed genetic diagnostic professionals in Australasia to assess their application of functional evidence in clinical practice.

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Purpose: Carbonic anhydrase IX (CAIX) is a well-established prognostic marker in breast cancer (BC). Nevertheless, this prognostic value is yet to be confirmed in BC subtypes. This study aims to investigate the prognostic effects of CAIX in oestrogen receptor (ER)-negative (ER-) BCs and to establish pathways related to cytoplasmic CAIX expression in ER- and lymph node-negative BCs.

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Muscle strength asymmetry and athlete introspective measures are associated with musculoskeletal (MSK) sport injury and reinjury. However, the interrelationship between mechanical and subjective measures of concentric and eccentric limb function needs further exploration. This includes investigating if an athlete's perception of their overall MSK function influences limb asymmetry across different testing modalities.

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Article Synopsis
  • Breast cancer continues to be a major global health issue, with increasing VUS complicating diagnosis in Australia’s healthcare system.
  • This study examined VUS data from 11 familial cancer centers, revealing that 4% of variants might be reclassified as pathogenic and 80% as benign.
  • Surveys indicated that there are challenges in VUS management due to limited resources, suggesting the need for routine reviews to improve patient care and communication between laboratories and cancer centers.
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