Publications by authors named "M R Maly"

Metals are essential components for the structure and function of many proteins. However, accurate modelling of their coordination environments remains a challenge due to the complexity and diversity of metal-coordination geometries. To address this, a method is presented for extracting and analysing coordination information, including bond lengths and angles, from the Crystallography Open Database.

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The prevalence of gastric NEN is estimated worldwide at 8.9% of all gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) and only 0.3%-1% of all gastric neoplasms, but is rising in the last decades.

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Article Synopsis
  • Tularemia, caused by the bacterium Francisella tularensis, poses a significant threat to human health but lacks extensive data on its distribution in blood-feeding arthropods.
  • A study conducted in the Břeclav district in 2022 screened various hematophagous vectors, including ticks, mosquitoes, and blackflies, to check for the presence of this bacterium.
  • The results revealed only two positive samples for F. tularensis subsp. holarctica, both from the tick species Dermacentor reticulatus, while no presence was found in mosquitoes or blackflies.
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Here, we present a modular synthesis as well as physicochemical and biological evaluation of a new series of amphiphilic dendrons carrying triphenylphosphonium groups at their periphery. Within the series, the size and mutual balance of lipophilic and hydrophilic domains are systematically varied, changing the dendron shape from cylindrical to conical. In physiological solution, the dendrons exhibit very low critical micelle concentrations (2.

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