Biotic stresses such as fungal pathogens significantly affect global crop yields. Understanding of the plant-pathogen interactions during root infection, especially in monocot crops, remains limited compared to fungal colonizations of dicots. The infection process of several cereal crop root-damaging fungi and oomycetes is highly similar to root infections by the pathogen model Phytophthora palmivora.
View Article and Find Full Text PDFBackground: Trace amine-associated receptor 1 (TAAR1) agonists offer a new approach, but there is uncertainty regarding their effects, exact mechanism of action and potential role in treating psychosis.
Aims: To evaluate the available evidence on TAAR1 agonists in psychosis, using triangulation of the output of living systematic reviews (LSRs) of animal and human studies, and provide recommendations for future research prioritisation.
Method: This study is part of GALENOS (Global Alliance for Living Evidence on aNxiety, depressiOn and pSychosis).
Rationale: Unrecognised coronary artery disease (CAD) may contribute to adverse outcomes in chronic obstructive pulmonary disease (COPD). Improved identification of at-risk groups could inform better preventative care. We aimed to evaluate the burden and relationships of radiologically detectable CAD in COPD, establish frequency of occult disease, and examine potential cardiovascular screening methods.
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