Mycopharmaceuticals from basidiomycetes represent a promising source of new antimicrobials to overcome the challenges of multidrug-resistant bacteria. Here we report for the first time the activity of aurisin A, a dimeric sesquiterpenoid isolated from wild bioluminescent basidiomycetes DSM 24013, against methicillin-resistant (MRSA). Aurisin A revealed strong anti-MRSA activity with minimum inhibitory concentration 7.
View Article and Find Full Text PDFComb Chem High Throughput Screen
April 2024
L., commonly known as Ḥulba or Methi in Unani medicine, is an annual self-pollinating plant belonging to the family. It has been utilized for centuries to treat a wide range of diseases, and modern research has supported its traditional medicinal claims.
View Article and Find Full Text PDFEthnopharmacological Relevance: Psoriasis, despite modern therapeutic options, is incurable and recurrent. In Unani (Greco-Arab) medicine, many medications and formulations have been prescribed by eminent scholars for conditions clinically similar to psoriasis, though empirical evidence is sparse. Hence, the experimental formulations ItrīfalShāhtra and MarhamḤina were chosen to be compared to the standard therapies PUVAsol and petrolatum for their safety and efficacy.
View Article and Find Full Text PDFThe paper presents the data from the surface and subsurface mapping of this area for the purpose of siting industrial city in the area. The field data collected combine with the borehole data was to successfully apply these to solving geological, environmental and engineering complications posed by the complexity of the subsurface geological structures underlain this area. The Electrical Resistivity, (ER) and Induced Polarization, (IP) data were initially processed using RES2DINV software model to generate the depth to the lithological units together with topographic correction.
View Article and Find Full Text PDFObjective: To investigate the hypoglycemic effect of the aqueous extract of Octomeles sumatrana (O. sumatrana) (OS) in streptozotocin-induced diabetic rats (STZ) and its molecular mechanisms.
Methods: Diabetes was induced by intraperitoneal (i.