Background: Achalasia is a rare oesophageal condition that can affect eating behaviours. This study aimed to evaluate the feasibility of recruitment and assess the acceptability of a co-designed, workbook-based intervention targeting one of the most challenging eating behaviours, which was eating in a social setting.
Methods: A mixed-method approach was employed, which involved pre- and post-intervention questionnaires and semi-structured interviews.
Snakebites are a significant health issue, especially in tropical and subtropical regions. Envenomation from snakebites is a clinical emergency requiring prompt treatment. Recently, a new species of blunt-nosed viper, , was identified in central and southern Iran through morphological and molecular studies.
View Article and Find Full Text PDFIncreasing efforts have been devoted to promoting sustainable demolition waste management (DWM) from a life cycle-thinking perspective. To this end, facilitating sustainability-oriented decision-making for DWM planning requires a sustainability assessment framework for assessing multifaceted criteria. This study develops a building information modelling (BIM)-based DWM sustainability assessment approach to facilitate the life cycle assessment (LCA) and decision-making by coupling the enriched Industry Foundation Classes model with hybrid multi-criteria decision-aiding (MCDA) methods using Dynamo visual scripting.
View Article and Find Full Text PDFThe design and development of wound-dressing hydrogels with desirable therapeutic effects and proper mechanical and self-healing properties are crucial in the healthcare sector. This research aims to prepare a new self-healing hydrogel based on Tragacanth, polyvinyl alcohol, and borax to be used as a wound dressing, the hydrogel was first prepared through a simple and one-pot reaction. The efficiency of the resulting product was then assessed based on the rheological and self-healing tests as well as cellular tests on a mouse fibroblast cell line (L929) including toxicity and scratch tests as well as the investigation of the expression of TGFβ1, TGFβ2, and VEGF-A gens (using Real-time PCR).
View Article and Find Full Text PDFKleefstra Syndrome (KS) is a rare genetic neurodevelopmental disorder caused by a microdeletion in chromosomal region 9q34.3 or a mutation in the euchromatin histone methyltransferase 1 (EHTM1) gene. Patients with KS show a range of clinical symptoms, including delay in motor and speech development, intellectual disability, autistic-like features, childhood hypotonia, and distinctive facial dysmorphic features.
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