Critical Steps To Address Climate, Health, And Equity.

Climate change poses an unprecedented threat to human health and well-being in the United States. In this article, part of the National Academy of Medicine's Vital Directions for Health and Health Care: Priorities for 2025 initiative, we outline key strategies to address climate change, health, and equity, using a public health approach. We focus on three critical areas: transitioning to clean energy sources, upgrading health infrastructure, and scaling public health and health care resilience.

Accuracy of Automatically Identifying the American Conference of Governmental Industrial Hygienists Threshold Limit Values Twelve Lifting Zones over Three Simplified Zones Using Computer Algorithm.

The American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Values (TLVs) for lifting provides risk zones for assessing two-handed lifting tasks. This paper describes two computational models for identifying the lifting risk zones using gyroscope information from five inertial measurement units (IMUs) attached to the lifter. Two models were developed: (1) the ratio model using body segment length ratios of the forearm, upper arm, trunk, thigh, and calf segments, and (2) the ratio + length model using actual measurements of the body segments in the ratio model.

Sodium Thiosulfate: An Innovative Multi-Target Repurposed Treatment Strategy for Late-Onset Alzheimer's Disease.

Late-onset Alzheimer's disease (LOAD) is a chronic, multifactorial, and progressive neurodegenerative disease that associates with aging and is highly prevalent in our older population (≥65 years of age). This hypothesis generating this narrative review will examine the important role for the use of sodium thiosulfate (STS) as a possible multi-targeting treatment option for LOAD. Sulfur is widely available in our environment and is responsible for forming organosulfur compounds that are known to be associated with a wide range of biological activities in the brain.

Pseudo-linkage or real-linkage of rust resistance genes in a wheat-Thinopyrum intermedium translocation line.

We analysed the chromosomal structures of two wheat-Thinopyrum intermedium addition lines Z4 and Z5 and resolved the linkage relationship between the leaf rust and stripe rust resistance genes in Z4. Wheat addition lines Z4 and Z5 carrying rust resistance genes from Thinopyrum intermedium (JJJJStSt, 2n = 6x = 42) together with three wheat lines involved in the production of these addition lines were analysed by rust response, 90K SNP genotyping, and molecular cytogenetic analysis. Seedling leaf rust (LR) responses to five diverse pathotypes indicated that the LR resistance gene(s) was located in translocation chromosome T3DS-3AS.