Porcine pericardial decellularized matrix bilayer patch containing adipose stem cell-derived exosomes for the treatment of diabetic wounds.

Chronic hard-to-heal wounds pose a significant threat to patients' health and quality of life, and their clinical management remains a challenge. Adipose-derived stem cell exosomes (ADSC-exos) have shown promising results in promoting diabetic wound healing. However, effectively enhancing the retention of exosomes in wounds for treatment remains a key issue that needs to be addressed.

The intestinal fungus Aspergillus tubingensis promotes polycystic ovary syndrome through a secondary metabolite.

Polycystic ovary syndrome (PCOS) affects 6%-10% of women of reproductive age and is known to be associated with disruptions in the gut bacteria. However, the role of the gut mycobiota in PCOS pathology remains unclear. Using culture-dependent and internal transcribed spacer 2 (ITS2)-sequencing methods, we discovered an enrichment of the gut-colonizable fungus Aspergillus tubingensis in 226 individuals, with or without PCOS, from 3 different geographical areas within China.

Public Health.

Background: The role of diet in modulating inflammation and its potential impact on cognition has raised attention. Additionally, recent research has addressed the disruption of the gut-brain axis in dementia development. This study aims to explore how the interactions between inflammatory diets and Helicobacter pylori (Hp) infection affect cognitive domains in older adults.

Dementia Care Research and Psychosocial Factors.

Background: Combined cognitive training and physical activity has been known to improve brain function. The purpose of this study is to investigate whether combined intervention affects the improvement of cognitive function in the community-dwelling elderly, and to determine if it improves physical function, such as motor speed and balance.

Method: The study was conducted among community-dwelling elderly aged 65 years.

Comprehensive evaluation of physio-morphological traits of alfalfa (Medicago sativa L.) varieties under salt stress.

Salt is a major abiotic factor significantly affecting plant growth and development. Alfalfa (Medicago sativa L.), a crucial perennial crop for livestock feed, shows significant differences in salt tolerance among different varieties.