Publications by authors named "M R Garcia-Sort"
Article Synopsis
- Advancements in treatment for ischemic stroke necessitate research using animal models that closely resemble human brain characteristics, specifically porcine (pig) brains.
- A new minimally invasive procedure was developed, using a guide catheter to induce focal cerebral ischemia in swine by occluding blood vessels similar to methods used in rodent models.
- After applying this technique, 7 out of 8 pigs showed significant brain damage within 90 minutes, leading to large cerebral infarctions while ensuring no fatalities during the process, indicating the model's potential for human stroke research.
Background The endovascular therapy for cerebral venous sinus thrombosis (CVST) is currently accepted as a second-line treatment for patients who have failed or those in whom systemic anticoagulation is contraindicated or in a subgroup of patients presenting with rapid neurologic deterioration. A number of different mechanical and pharmacologic endovascular strategies have been reported, either as separate or combined approaches. These new catheters and aspiration systems have a high power and vacuum capacity, which carries a risk of anemization of the patient and hypovolemic shock, being necessitating the transfusion of the patient.
View Article and Find Full Text PDFBackground Intracranial wide-neck aneurysms at the arterial bifurcations, especially in the aneurysms where the bifurcating branches emanate directly from the base of the aneurysm, have been particularly difficult on which to perform endovascular treatment. The 'Y'-configuration, double stent-assisted coil embolization is an option for the treatment of these difficult aneurysms, allowing the closure of the aneurysm, preserving the parent arteries. Material and methods In a nine-year period, 546 intracranial aneurysms in 493 patients were treated at our center by endovascular approach.
View Article and Find Full Text PDFBackground: The use of retrievable stents for endovascular clot retrieval has dramatically improved successful revascularization and clinical outcome in selected patients with acute stroke.
Objective: To describe the rate and clinical consequences of unwanted spontaneous detachment of these devices during mechanical thrombectomy.
Methods: We studied 262 consecutive patients treated with the retrievable stent, Solitaire, for acute ischemic stroke between November 2008 and April 2015.