Publications by authors named "M R Galdiero"

Article Synopsis
  • Neutrophils, the most common type of white blood cells, play a significant role in inflammation and are present in greater levels in patients with psoriatic arthritis (PsA), a chronic disease affecting joints and other body systems.
  • A study involving 31 PsA patients and 22 healthy controls investigated the function of neutrophils from blood samples; these neutrophils were tested for various activation and response characteristics.
  • Results showed that neutrophils from PsA patients had lower activation and effectiveness when responding to stimuli, along with elevated serum levels of inflammatory markers, suggesting a compromised immune response in these patients.
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Food plant diversity in bioactive compounds makes them an exploitable resource in the search for effective natural products to prevent or treat viral infections. Therefore, in the framework aimed at studying the antiviral properties of extractive mixtures from fruits (and their waste) grown in the Campania Region (Italy), jujube drupes ( Mill.) were our focus.

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() is a plant widely used for its beneficial properties both in medical and non-medical fields. Because they produce bioactive metabolites, plants are a major resource for drug discovery. In this study, two different cultivars of leaves of (Salento and Barletta) were obtained by maceration or microwave-assisted extraction (MAE).

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The growing threat of viral infections requires innovative therapeutic approaches to safeguard human health. Nanomaterials emerge as a promising solution to overcome the limitations associated with conventional therapies. The eco-friendly synthesis of silver nanoparticles (AgNPs) currently represents a method that guarantees antimicrobial efficacy, safety, and cost-effectiveness.

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The innate immune system, composed of neutrophils, basophils, eosinophils, myeloid-derived suppressor cells (MDSCs), macrophages, dendritic cells (DCs), mast cells (MCs), and innate lymphoid cells (ILCs), is the first line of defense. Growing evidence demonstrates the crucial role of innate immunity in tumor initiation and progression. Several studies support the idea that innate immunity, through the release of pro- and/or anti-inflammatory cytokines and tumor growth factors, plays a significant role in the pathogenesis, progression, and prognosis of cutaneous malignant melanoma (MM).

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