Publications by authors named "M R Gago"
Background: The Movement Disorder Society Non-Motor Rating Scale (MDS-NMS) serves as a comprehensive clinical assessment tool for non-motor symptoms in Parkinson's disease (PD) OBJECTIVES: This study aims to validate the Portuguese version of the MDS-NMS, addressing the critical need for culturally adapted rating scales in Portuguese-speaking populations.
Methods: This multicenter, cross-sectional study engaged native Portuguese-speaking PD patients from 16 Movement Disorders Centers across Portugal and Brazil. We conducted a meticulous translation process into Portuguese, including forward-backward translation and cognitive pretesting.
Living with Parkinson's disease in Portugal: Findings from PRISM study.
Parkinsonism Relat Disord
November 2024
Article Synopsis
- Parkinson's disease (PD) is a serious brain illness, and a study called PRISM looked at how it affects patients in Portugal, including their health and how they live their lives.
- In the study of 80 Portuguese PD patients, many were men around 66 years old, and they often dealt with depression and anxiety.
- The research showed that most patients took a common medication called Levodopa and had a harder time enjoying life, with many needing mental health help and some even retiring early from their jobs.
Effects of the ActiveHip+ mHealth intervention on the recovery of older adults with hip fracture and their family caregivers: a multicentre open-label randomised controlled trial.
EClinicalMedicine
July 2024
Article Synopsis
- Mobile health (mHealth) systems were tested to improve rehabilitation for older adults with hip fractures and to support their caregivers, as many don't fully recover post-injury.
- A randomized controlled trial in Andalusia involved 105 patients aged 65+, comparing a 12-week ActiveHip + mHealth intervention to usual care, assessing physical performance at various time points.
- Results showed the intervention group had significantly better physical performance 3 months post-surgery but did not maintain these improvements at the 1-year follow-up, indicating a potential need for ongoing support.
Introduction: Parkinson's disease (PD) is a neurodegenerative disorder commonly characterized by motor impairments. The development of mobile health (m-health) technologies, such as wearable and smart devices, presents an opportunity for the implementation of clinical tools that can support tasks such as early diagnosis and objective quantification of symptoms.
Objective: This study evaluates a framework to monitor motor symptoms of PD patients based on the performance of standardized exercises such as those performed during clinic evaluation.
Background: Iron content is increased in the substantia nigra of persons with Parkinson's disease and may contribute to the pathophysiology of the disorder. Early research suggests that the iron chelator deferiprone can reduce nigrostriatal iron content in persons with Parkinson's disease, but its effects on disease progression are unclear.
Methods: We conducted a multicenter, phase 2, randomized, double-blind trial involving participants with newly diagnosed Parkinson's disease who had never received levodopa.