Objective: Achieving near normal vision following unilateral congenital cataract surgery is possible but requires early surgery, optical correction and consistent patching. Patching is often challenging for children and their caregivers. The goal of these analyses is to examine the association between reported consistency in patching during the first year after surgery and visual acuity.
View Article and Find Full Text PDFPurpose: The goal of these analyses is to provide evidence that can help parents and healthcare providers determine whether or not to continue occlusion therapy once a reliable measure of optotype acuity can be obtained in children who are born with a unilateral congenital cataract.
Design: Data from the Infant Aphakia Treatment Study (IATS) are used in a cohort design.
Participants: A total of 105 children who participated in the IATS and did not have a vision-threatening adverse event.
Plastic pollution in aquatic ecosystems is increasing and plastic particles may adsorb and transport a diverse array of contaminants, thereby increasing their bioavailability to biota. This investigation aimed to evaluate the effects of varying polyethylene microplastics (PE MPs) and naphthalene (NAPH) concentrations on the survival and feeding rates of the model organism, Artemia salina, as well as NAPH adsorption to microplastics at different salinity levels (17, 75, 35.5 and 52.
View Article and Find Full Text PDF: Selenium deficiency represents a risk factor for the occurrence of severe diseases, such as acute kidney injury (AKI). Recently, selenoprotein-p1 (SEPP1), a selenium transporter, mainly released by the liver, has emerged as a promising plasmatic biomarker of AKI as a consequence of cardio-surgery operations. The aim of the present study was to investigate, on an in vitro model of hypoxia induced in renal tubular cells, HK-2, the effects of sodium selenite (NaSeO) and to evaluate the expression of SEPP1 as a marker of injury.
View Article and Find Full Text PDFImportance: Parents may be concerned about the adverse outcomes of occlusion therapy in children treated for unilateral congenital cataract (UCC).
Objective: To determine whether occlusion therapy in children treated for UCC with poor visual outcomes is negatively associated with poorer child and/or family functioning.
Design, Setting, And Participants: This cohort study was conducted in 2023 using data collected between 2006 and 2016 in the Infant Aphakia Treatment Study (IATS).