Randomized clinical trial of vitamin D3 doses on prostatic vitamin D metabolite levels and ki67 labeling in prostate cancer patients.

Context: Vitamin D3 might benefit prostate cancer (PCa) patients because prostate cells can locally synthesize the active hormone calcitriol.

Objective: Our objective was to determine the effects of oral vitamin D3 on vitamin D metabolites and PCa proliferative activity in prostate tissue.

Design And Setting: We conducted a double-blind randomized clinical trial at surgical oncology clinics in Toronto, Canada.

Comparative study of baccalaureate nursing student self-efficacy before and after simulation.

Evaluation of learning and the development of prelicensure nursing education include an exploration of new teaching models and techniques for student learning assessment. The utilization of high-fidelity human simulation in nursing provides nursing faculty and students the opportunity to expand the boundaries of conventional learning from an instructional paradigm to a blending of modalities that enrich the student experience and provide an avenue for self-determined learning. The inception of computer-generated high-fidelity human simulation technology into the undergraduate nursing curriculum generated this correlation study, which examined two separate groups of senior baccalaureate nursing students' reported self-efficacy for providing family-centered care.

United we stand: preparing nursing students for political activism.

Political activism for healthcare workers is a crucial complement to clinical practice. Nurses are in a unique position to not only provide bedside care but also to advocate for change within the political arena and the community at large. Preparing professional nurses for community-based practice involving political activism and civic engagement requires developing and sustaining a philosophy that supports service learning and community partnerships.

Laparoscopic repair of traumatic gastric perforation using a gasless technique.

Laparoscopy has been used in the evaluation of injuries secondary to blunt and penetrating trauma. In this case report, we describe the use of a new gasless laparoscopic technique using conventional instruments to successfully evaluate and repair a traumatic gastric perforation.