Hyperspectral imaging reveals that sapropelic mud therapy may improve local tissue oxygenation in elderly.

Sapropelic muds have been used for centuries to treat various illnesses, but their effects and mechanisms are still under research. In this study the effects of Techirghiol sapropelic mud on tissue oxygenation in elderly patients diagnosed with neuromuscular disorders were investigated using spatial and spectral information provided by hyperspectral imaging technique. A group of 38 elderly patients with neuromuscular disorders for which they received mud therapy was studied.

Predictive factors regarding bullying behavior in Romanian schools.

Introduction: The present study investigates the phenomenon of bullying in schools in the city of Constanta, Romania.

Method: From the age point of view, we have had  = 210 12-year-old subjects and 193 13-year-old subjects, and from the biological gender point of view, there were 234 girls and 169 boys. The study's main objective was to investigate aggressive behavior in adolescents in a school context.

VCAM-1 targeted nanocarriers of shRNA-Smad3 mitigate endothelial-to-mesenchymal transition triggered by high glucose concentrations and osteogenic factors in valvular endothelial cells.

Endothelial to mesenchymal transition (EndMT) of valvular endothelial cells (VEC) is a key process in the development and progression of calcific aortic valve disease (CAVD). High expression of the Smad3 transcription factor is crucial in the transition process. We hypothesize that silencing Smad3 could hinder EndMT and provide a novel treatment for CAVD.