Publications by authors named "M R C Luijten"

Background: The FAIR (Findable, Accessible, Interoperable, Reusable) data principles are a guideline to improve the reusability of data. However, properly implementing these principles is challenging due to a wide range of barriers.

Objectives: To further the field of FAIR data, this study aimed to systematically identify barriers regarding implementing the FAIR principles in the area of child and adolescent mental health research, define the most challenging barriers, and provide recommendations for these barriers.

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  • In human health risk assessment, genotoxicity hazards of chemicals typically start with a set of in vitro tests, but these tests don't capture all potential genotoxic endpoints, leading to sometimes contradictory results.
  • Mathematical modeling can improve the interpretation of these tests by accounting for each test's strengths and weaknesses, providing objective predictions with associated uncertainties.
  • A study found that combining a mammalian in vitro clastogenicity test and a gene mutation test offers strong evidence for genotoxic hazard assessment, but the bacterial reverse mutation (Ames) test alone can still provide useful evidence when no other data is available.
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Background: The COVID-19 pandemic negatively affected child and adolescent mental health and at the end of the pandemic (April 2022) child mental health had not returned to pre-pandemic levels. We investigated whether this observed increase in mental health problems has continued, halted, or reversed after the end of the pandemic in children from the general population and in children in psychiatric care.

Methods: We collected parent-reported and child-reported data at two additional post-pandemic time points (November/December 2022 and March/April 2023) in children (8-18 years) from two general population samples ( = 818-1056 per measurement) and one clinical sample receiving psychiatric care ( = 320-370) and compared these with data from before the pandemic.

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  • The study looked into whether patients change their answers on surveys about their health when they know doctors will read them.
  • Researchers compared two groups of patients: one that knew their answers would be seen by doctors and another that didn't.
  • The results showed no big differences in answers between the two groups, suggesting it's okay for doctors to use these surveys to help understand patients' needs.
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Adults with attachment insecurity often struggle in romantic relationships due to difficulties in emotion regulation (ER). One potentially influential yet understudied factor is the inflexible over-reliance on either intrapersonal (self-directed, e.g.

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